No. They involve different applications and government charges, and a domestic change of status may still be followed by a consular visa application for later travel. Budget for the actual anticipated sequence.
Keep procedure costs outside the investment total
Identify principal and dependent filings, professional preparation, document work and possible travel expenses. Check current official charges and any optional service requirements rather than quoting one universal E-2 fee. The enterprise’s capital commitment remains a separate eligibility issue.
Selecting a route does not change which business funds qualify or turn immigration expenses into a guaranteed investment threshold. Overruns here come from repeating a step rather than from underestimating one. A domestic change of status followed by an unplanned trip abroad means funding a consular application as well; an incomplete investment record means preparing the enterprise evidence twice; a refusal touching marginality means funding the business further before anything can be resubmitted.
Hypothetical example: an education data analytics start-up budgets for a single filing and ends up paying for a second, fuller evidentiary package after its first submission described a plan rather than an operating business. Work out which of these repeats is plausible in your own circumstances and price it as a contingency, held clearly outside the capital figure, which is an eligibility question and never a budget line.