It can, if the evidence establishes special or advanced knowledge and the U.S. role involves that knowledge. USCIS does not require proprietary or unique knowledge, but ordinary familiarity with widely used technology is insufficient by itself.
Identify what goes beyond general skill
Explain the organisation’s implementation, processes or products and the employee’s developed understanding of them. Support the distinction with training, work history and specific assignments. The petition must still establish the related-business structure and qualifying foreign employment.
Removing a proprietary-only assumption does not remove the specialised-knowledge standard. Nothing in the standard requires the knowledge to be patented, secret or unique, so the question is not whether others could in principle acquire it but whether this employee's knowledge is special or advanced in the relevant sense. Frame the case around what distinguishes their capability from that of a competent professional in the field.
Useful markers include the depth of the application, the organization's own way of doing things, the accumulation of context that only comes from working within the business, and responsibility for outcomes rather than tasks. Avoid claiming exclusivity that cannot be supported, since an overstated assertion tends to be tested and its failure colours the rest. Remember too that the corporate relationship and the continuous year of qualifying employment abroad within the preceding three years remain separate requirements that this argument does not address.